Corneal Epithelial Stem Cell and Disease – Past, Present and Future
نویسنده
چکیده
Differential microarray experiments have shown that there are 186 transcripts predominantly overexpressed in the limbus, 644 in the cornea and 506 in the conjunctiva of the vervet monkey. In humans, 332 and 592 transcripts are predominantly overexpressed in the conjunctival and corneal epithelia, respectively. Mounting evidence generated from clinical observations and experimental animal studies over the last three decades strongly suggests that corneal epithelial stem cells locate at the limbus. More specifically, the interpalisadal epithelial rete ridges in the palisades of Vogt may serve as a repository for limbal stem cells (LSCs).
منابع مشابه
Comparison of Ultra Structure and Gene Expression of Cultured Limbal Stem Cells and Fresh Conjunctival, Limbal and Corneal Tissues
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